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While intriguing, these benefits lack robust clinical backing, and their consistency is uncertain
Not surprisingly, some of the pharmacokinetic parameters obtained from this study differed from those obtained by Larson, et al .[51] In the current study, the median C max was 1.47 ng/ml, with the highest rapamycin blood concentration measured being 2.13 ng/ml
The proposed mechanism includes modulation of oxidative stress and mitochondrial biogenesis
the clinical benefit is unproven [1]
Its safety profile is well-established over decades of clinical use
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